Granite and quartzite; can you tell the difference? There is a pretty good chance that you cannot. It takes a trained eye to know which is which. That is an exciting fact for homeowners that want granite countertops but not the granite issues. Here are some of the major differences between granite countertops and quartzite countertops. Slightly Different Molecular Structure During Formation of the Stone The granules of crystals found in granite tend to be smaller.